Laboratory of Structural and Supramolecular Chemistry

Fax: +30 210 6511766 


Lab Director
Dr. Irene Moustakali-Mavridis,  Researcher A, Tel: +30210-6503793, 

Dr. Konstantina Yannakopoulou , Researcher A, Tel: +30210-6503796, 

Honorary Research Associate
Dr.Eugene Hadjoudis, 

Research Associates
Dr. Davide Mafffeo,
Dr. Anastasia Paulidou
Dr. Emmanuel Saridakis

Graduate Students
Chrysa Aggelidou
Petros Giastas
Spyros Hadjieythymiou
Lasse Kyllonen
Maria Lamropoulou

Former Group members
PhD: Aliki Rontoyianni, Kiki Eliadou, Stella Makedonopoulou, Nikos Pinotsis Nikos Mourtzis
MSc: Dimitris Zouvelekis, Penny Stefanidou
Post-Doc: Zoi Plyta

Participating in the networks
Network of Excellence Nano2Life
Marie Curie RTN Uninanocups

Research Facilities
Single Crystal Diffractometer (Siemens, upgrated by X-ray Logic). Macromolecular Crystallography Laboratory (Dr. I. M. Mavridis, Coordinator): Rotating anode (Rigaku), Image Plate Raxis IV (Molecular Structure corporation), Low Temperature apparatus (Oxford Cryosystems), computing and molecular graphics facilities, Circular Dichroism spectrometer (Jasco J-715).

NMR Laboratory: 500 MHz Avance DRX Bruker, 250 MHz AC Bruker, (In-Charge Scientist Dr. K. Yannakopoulou, IPC)

Miscellaneous Departmental Facilities

 Research Activities

The laboratory has been involved in Supramolecular Structures of Cyclodextrins with small and large molecules. Cyclodextrins are cyclic sugars commonly composed of 6, 7, or 8 glucose units called , , -cyclodextrins, respectively.


Viewed from the side, their shape resembles a trancated cone with a relatively hydrophobic cavity and a hydrophilic exterior, the multifunctional primary (upper) and secondary (lower) faces lined with OH groups. A plethora of hydrophobic molecules are encapsulated in the cavity forming inclusion complexes. The above in combination with the fact that they are natural, water soluble compounds makes them candidates for many applications, especially as carriers for pharmaceutical compounds. Cyclodextrin host -guest systems have many characteristics of receptor-substrate systems and they have been used as models for catalysis. They have been used also as models for non-bonding interactions and H-bonding, usually with water molecules. Finally, cyclodextrins and their inclusion complexes have the ability to self assemble forming organized supramolecular systems.  

The groups research based on cyclodextrins has acquired many and different directions:

    Selected Publications 

    Last Updated: Apr.26, 2005