Selected Publications
  • "Inhibition of Topoisomerase I by Naphthoquinone Derivatives", Vassilios P. Papageorgiou, Tianhu Li, Zoi F. Plyta, Antonios S. Mellidis, Andreana N. Assimopoulou, Emmanuel N. Pitsinos, and Elias A. Couladouros
    Bioorg. Med. Chem. Letters 1998, 8(23), 3385–3390.
  • "Total Synthesis of Combretastatins D", Couladouros, E. A.; Soufli, I. C.; Moutsos, V. I.; Chadha, R. K.
    Chem. Eur. J. 1998, 4, 33-43.
  • "The Chemistry and Biology of Alkannin, Shikonin and Related Naphthazarin Natural Products", Papageorgiou, V. P.; Assimopoulou, A. N.; Couladouros, E. A.; Hepworth, D.; Nicolaou, K. C.
    Angew. Chem. Int. Ed. 1999, 38, 270-300.
  • "1,4-Reductive Addition of Hydrazoic Acid on γ-Keto-α,β-Unsaturated-δ-Lactones and Lactames: A Convenient Route to Enaminoketo δ-Lactones and Lactames", Koulocheri, S. D.; Haroutounian, S. A.; Apostolopoulos, C. D.; Chada, R. K.; Couladouros, E. A.
    Eur. J. Org. Chem.     1999, 1449-1453.
  • " A General Synthetic Route Towards γ- and-δ-Lactones. Total Asymmetric Synthesis of (-)-Muricatacin and the Mosquito Oviposition Pheromone (5R, 6S)-6-Acetoxy-hexadecanolide", Couladouros, E. A.; Mihou, A. P.
         Tetrahedron Lett. 1999, 40, 4861-4862.
  • "A general synthetic route towards bastadins. Part 1: Synthesis of the eastern part of bastadins 4-16", Couladouros, E. A.; Moutsos, V. I.
    Tetrahedron Lett. 1999, 40, 7023-7026.
  • "A general synthetic route towards bastadins. Part 2: Synthesis of the western part of bastadins 4-16, and fully functionalized macrocycle of bastadin 12", Couladouros, E. A.; Moutsos, V. I.
    Tetrahedron Lett. 1999, 40, 7027-7030.
  • "Stabilization of Microtubules by Combretastatin D Derivatives", Couladouros, E. A.; Li, T.; Moutsos, V. I.; Pitsinos, E. N.; Soufli, I. C.
    Biοorg. Med. Chem. Letters 1999, 9, 2927–2928.
  • "Biomimetic Explorations Towards the Bisorbicillinoids. Total Synthesis of Bisorbicillinol, Bisorbibutenolide and Trichodimerol", Nicolaou, K. C.; Simonsen, K. B.; Vassilikogiannakis, G.; Baran, P. S.; Vidali, V. P.; Pitsinos, E. N.; Couladouros, E. A.
    Angew. Chem. Int. Ed. 1999, 38, 3555–3559.
  • "Biomimetic Total Synthesis of Bisorbicillinol, Bisorbibutenolide, Trichodimerol, and Designed Analogues of Bisorbicillinoids", Nicolaou, K. C.; Vassilikogiannakis, G.; Simonsen, K. B.; Baran, P. S.; Zhong, Y.-L.; Vidali, V. P.; Pitsinos, E. N.; Couladouros, E. A.
    J. Am. Chem. Soc. 2000, 122, 3071–3079.
  • "Vicinal Tetraamines of Defined Geometry: Potential Scaffolds for Assembly", Emmanuel N. Pitsinos, Jean-Marie Lehn and Andrι De Cian
    Helv. Chim. Acta 2001, 84, 22–31.
  • "Heterofunctional Linking Agents for the Synthesis of Well-Defined Block Copolymers of Dimethylsiloxane and tert-Butyl Methacrylate or 2-Vinylpyridine", Vasilios Bellas, Hermis Iatrou, Emmanuel N. Pitsinos, and Nikos Hadjichristidis
    Macromolecules 2001, 34, 5376–5378.
  • "Liquid Crystals Resulting from Combined Ionic and Hydrogen Bonding Interacrions of Nucleobase Derivatives", D. Tsiourvas, A.P. Mihou, E.A. Couladouros, C.M. Paleos
    Mol. Cryst. Liq. Cryst. 2001, 363, 177-184.
  • "A Convenient Route to Alkaloid Lipids: Application for the Synthesis of a Leptophylline A Analogue", Sofia D. Koulocheri, Emmanuel N. Pitsinos, Serkos A. Haroutounian
    Synthesis 2002, 111–115.
  • "An Expedient Asymmetric Synthesis of a Calystegin B4 Analogue", Sofia D. Koulocheri, Emmanuel N. Pitsinos, Serkos A. Haroutounian
    Synthesis 2002, 1707–1710.
  • "A Novel 2΄-(N-Methylpyridinium Acetate) Prodrug of Paclitaxel Induces Superior Antitumor Responses in Preclinical Cancer Models", Wolfgang Wrasidlo, Gerhard Gaedicke, Rodney Kiplin Guy, Johanne Renaud, Emmanuel N. Pitsinos, Kyriaco C. Nicolaou, Ralph A. Reisfeld, and Holger N. Lode
    Bioconjugate Chemistry 2002, 13, 1093–1099.
  • "A new efficient route for multigram asymmetric synthesis of alkannin and shikonin”, Couladouros, E.A.; Strongilos, A.T.; Papageorgiou, V.P.; Plyta, Z.F.
    Chem., Eur. J. 2002, 8, 1795–1803.
  • "Synthesis of hydroxylated naphthoquinone derivatives", Couladouros, E.A.; Strongilos, A.T.
    Eur. J. Org. Chem. 2002, 19, 3341–3350.
  • "Generation of libraries of pharmacophoric structures with increased complexity and diversity by employing polymorphic scaffolds", Couladouros, E.A; Strongilos, A.T.
    Angew. Chem. Int. Ed. 2002, 42(19), 3677-3680.
  • "Synthetic Studies Towards Trichodimerol and Related Vertinoid Polyketides", Emmanuel N. Pitsinos, Veroniki P. Vidali, Elias A. Couladouros
    ARKIVOC 2002, 13, 105–110.
  • "Synthesis and Evaluation of Three Novel Scyphostatin Analogues as Neutral Sphingomyelinase Inhibitors", Emmanuel N. Pitsinos, Veit Wascholowski, Sevasti Karaliota, Chrisoula Rigou, Elias A. Couladouros, Athanassios Giannis
    ChemBioChem 2003, 4(11), 1223–1225.
    •